About Vasculitis

Polymyalgia Rheumatica

Download this page as a PDF

What is Polymyalgia Rheumatica?

Polymyalgia Rheumatica (PMR) is an inflammatory disorder. It is frequently linked to Giant Cell Arteritis (GCA) occurring in 50 per cent of patients with GCA. Approximately 15 per cent of PMR patients develop GCA.

Who are affected?

The disease is usually diagnosed in patients over the age of 65. It is rarely seen in patients younger than 50. Women are twice as likely to develop PMR as men.

What is the aetiology (cause)?

The cause of PMR is not yet known.

What are the symptoms?

The symptoms usually come on over a few days. Symptoms include aching muscles and morning stiffness in the shoulders, hips, neck and mid-body. Other symptoms reported include: general tiredness, weakness, weight loss, low grade fever. Inflammation of the bones and joints can cause difficulty moving. Some patients develop swelling or fluid retention (oedema) of the hands, wrists, ankles and top of the feet.

normal shoulder joint and inflammation of shoulder joint

Making a diagnosis

There are no specific tests for PMR. Blood tests may show evidence of inflammation. Ultrasound and Positron emission tomography (PET scanning) have been used to confirm PMR inflammation. Patients with only PMR do not have the symptoms of GCA therefore a biopsy of the temporal artery (necessary in GCA) is unnecessary in PMR.


Moderate to high doses of steroid drugs (prednisolone) improve the symptoms of PMR. The effective dose is maintained for several weeks after the symptoms have resolved. Then it is gradually lowered and stopped. Careful monitoring is required in case the symptoms recur.

Where long term use of steroids or side effects occur the use of Methotrexate may allow the dose of steroid to be reduced. Ibuprofen (an anti-inflammatory drug) can be used to reduce painful symptoms, especially when the symptoms are only mild.

Drugs and Side effects

For information on the main drugs prescribed for Polymyalgia Rheumatica see:

For information on other drugs used in the treatment of vasculitis see Glossary of drugs and side effects.


Relapse occurs in 25 to 50 per cent of patients. This is more likely if the steroid dose is reduced too quickly. Relapse requires restarting or increasing the steroid dose. In most cases the symptoms will cease within one month to one year. The steroids can then be discontinued.

Key Points

  • PMR is sometimes associated with Giant Cell Arteritis
  • Treatment is usually with steroids
  • Treatment may be able to be stopped once the disease is controlled.

Related Vasculitis Articles

Further reading

Useful links

Our Useful Vasculitis Links page contains contact details for organisations offering help and support for patients with Polymyalgia Rheumatica, Giant Cell Arteritis and other vasculitis diseases.

Vasculitis Patient Symposium 2015


Autumn Newsletter 2015 Now Online

28 Nov 2015

Our latest newsletter is now online

Join DCVAS to support Vasculitis Research

20 Nov 2015

DCVAS have extended the registration until Decemeber 2017

New in the Vasculitis UK Shop...

17 Nov 2015

Items promoting awareness of Vasculitis, and our own Christmas Cards


Merseyside, Cheshire, and North Wales Support Group meeting

04 Dec 2015

The Merseyside, Cheshire, and North Wales Support Group are meeting in Liverpool

Christmas Tree Festival St Faiths Waterloo Merseyside

06 Dec 2015

Christmas Tree and Craft Stall Supporting Vasculitis UK

Christmas Tree Festival in the Peak District

10 Dec 2015

Christmas Tree Festival in the Peak District

Vasculitis East Midlands Christmas Lunch

12 Dec 2015

East Midlands Support Group Christmas Lunch

Winslow United v Buckingham Athletic to raise money for Sports Shots

28 Dec 2015

Sport Shots are fundraising for Vasculitis UK & Macmillan Cancer

Copyright©2015 Vasculitis UK. All Rights Reserved.
Design & Hosting by On Screen