About Vasculitis

Diseases Affecting Small Blood Vessels

small vessels

The diseases that affect the small vessels include some of the most common types of vasculitis. They are often divided into the diseases where anti-neutrophil cytoplasm antibodies (ANCA) are found in the blood (ANCA associated vasculitis) and diseases where ANCA is not found. The ANCA associated vasculitides are Wegener's granulomatosis (now called Granulomatosis with Polyangiitis) Microscopic Polyangiitis and Churg-Strauss syndrome (now called Eosinophillic Granulomatosis with Polyangiitis).

Many of the small vessel diseases can cause damage to the kidneys and prevent them working. The typical symptoms of impaired kidney function would be fatigue, poor appetite, and swollen legs and breathlessness due to retention of fluid. In severe cases acid and toxins accumulate in the body causing severe breathlessness, nausea and vomiting, confusion and epileptic fits. The blood pressure may also be very high which can cause damage to the kidneys, heart, brain and other organs.

Any patient with vasculitis should have the urine tested for blood and protein using a dipstick test. The presence of blood and protein can indicate inflammation in the kidneys and requires urgent assessment (within a few days) by a kidney specialist and may need a kidney biopsy. If not treated urgently inflammation in the kidneys can cause permanent damage needing dialysis treatment or kidney transplantation.

In the early stages of kidney inflammation the blood tests of kidney function (creatinine and estimated glomerular filtration rate (eGFR)) may still be normal - this is the best time to treat before significant damage has occurred.

eurordis logo

News

New Privacy Policy & Procedure

30 May 2018

Places Available for the Great South Run

15 Apr 2018

Places available through VUK

Rare Autoimmune Rheumatic Diseases Alliance

12 Apr 2018

RAIRDA Autoimmune Rheumatic Disease Alliance

Events

Climbing Snowdon

26 Jun 2018

3 Peaks Challenge

14 Jul 2018

Llyn Peninsular Trek

23 Jul 2018

White Collar Boxing

28 Jul 2018

Tough Mudder Half Run Yorkshire

28 Jul 2018

Aimee Crossland is taking part in Tough Mudder for VUK

Copyright © 2018 Vasculitis UK. All Rights Reserved. Whilst we make every effort to keep up to date, any information that is provided by Vasculitis UK should not be a substitute for professional medical advice. Always seek the opinion of your GP or other qualified medical professional before starting any new treatment, or making changes to existing treatment.
Design & Hosting by On Screen